Lidocane Hydrochloride

5.23 Lidocane Hydrochloride
 
 

CLASS
Antiarrhythmic agent, Antidysrhythmic (class Ib)
Local anesthetic, Topical

ACTIONS

INDICATIONS
To be used during intubation of patients with possible ICP or reactive airway disease.

Used to assist in the implementation of the easy IO.

CONTRAINDICATIONS

  • Allergy to caine related anesthetics
  • Severe heart block
  • Bradycardia unless pacemaker is in place
  • WPW (Wolff-Parkinson-White syndrome)
  • Pregnancy
  • Use with caution in hypovolemic and cardiogenic shock

ADVERSE REACTIONS AND SIDE EFFECTS
Administration of Lidocaine may cause lightheadedness, confusion, blurred vision, hypotension, cardiovascular collapse, bradycardia, CNS depression (altered level of consciousness, slurred speech, irritability, muscle twitching, seizures) with high doses
and localized anesthetic effects.

WARNINGS
Pregnancy safety: Category B.

Possible medication interactions that may occur:

  • Metabolic clearance of lidocaine may be decreased in patients taking beta-adrenergic blockers or in patients with liver dysfunction.
  • Apnea induced with succinylcholine may be prolonged with large doses of lidocaine.
  • Cardiac depression may occur if lidocaine is given concomitantly with IV phenytoin.
  • Additive neurological effects may occur with procainamide.

DOSAGE
ET purpose: 1.5 mg/kg for onset within 45 - 90 seconds

IO purpose: inject 1% Lidocaine into s.q. area of IO insertion site. Enough Lidocaine should be given to make slight skin bleb prior to IO insertion